English: Chemical structure of sebacic acid. The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. Structure Search. The Global Sebacic Acid Market will grow by USD 129.57 mn during 2020-2024 The EC or list number is the primary substance identifier used by ECHA. Note that for readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed. Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or the. 8.24. Molecular structure. Beilstein/REAXYS Number 1210591 . Sebacic acid is a naturally occurring dicarboxylic acid with the structure (CH₂)₈. In a process said to be operated in Britain1 castor oil is subjected to alkaline fusion under critically controlled conditions to produce a mixture of methyl hexyl ketone and ω-hydroxydecanoic acid. Azelaic acid is made by the ozonolysis of another natural product, oleic acid: Sebacic acid is used for nylon 610 and azelaic acid for nylon 69. Please note: Precautionary measures and guidance on safe use concern the use and handling of the specific substance as such, not of the presence of the substance in other articles or mixtures. In another study, Hu et al. Sebacic acid Accession Number DB07645 Description Not Available Type Small Molecule Groups Experimental Structure. The InfoCard summarises the non-confidential data of a substance held in the databases of the European Chemicals Agency (ECHA). If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. The Waste Framework Directive aims to protect the environment and human health from the generation and management of waste and to improve efficient use of resources. Release to the environment of this substance can occur from industrial use: formulation of mixtures, in processing aids at industrial sites, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, manufacturing of the substance and formulation in materials. PA1010 is semicrystalline, which is the reason for its high mechanical resistance and chemical stability. Sebacic acid is an alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. It is frequently used as extruded monofilament. ... Sebacic acid, compound with hexane-1,6-diamine (1:1) EC Inventory . Properties of Evonik Degussa AG Vestamid® Terra DS (Medium Viscosity) PA101023, Kaneyoshi Ashida, ... Kadzuo Iwasaki, in Handbook of Plastic Foams, 1995. This substance is used in the following areas: formulation of mixtures and/or re-packaging. We apologise for the inconvenience in the meantime. 4.13. Adipic acid is partially esterified to the monomethyl adipate. Sebacic dihydrazide. This information is only displayed if the substance is well–defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. Articles of Sebacic acid are included as well. First-aid measures Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its … Heating must be rapid and even and any tendency to preheating must be avoided. Sebacic Acid Safety Data Sheet According to Federal Register / Vol. All mass spectra in this site (plus many more) are available from the NIST/EPA/NIH Mass Spectral Library. Due to the rising demand, there is a further production in France. The purpose of the information provided under this section is to highlight the substance hazardousness in a readable format. Substances may have impurities and additives that lead to different classifications. 250°C, so that saponification, leading to the formation of ricinoleic acid; is followed by a reaction giving sebacic acid and octan-2-ol Figure 18.5. 5). If generated, an InChI string will also be generated and made available for searching. Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. An increase of 800 times was observed when the sebacic acid concentration reached 80%. Synthesized materials possess good mechanical properties, elasticity, and surface erosion biodegradation behavior. Polyamide 1010 is the polycondensation product of 1,10-decamethylene diamine and 1,10-decanedioic acid (sebacic acid) as shown in Fig. 4.3), a C-20 chain fatty acid, has also been evaluated to promote the acquisition of the brown adipocyte morphology, thereby facilitating a coordinate induction of the mRNAs for GLUT4 gene markers of brown adipocyte differentiation (Schluter et al., 2002, pp. This substance is used for the manufacture of: chemicals, plastic products and rubber products. Oligomerization can occur during the synthesis of the methacrylated monomer, and oligomerization occurs to a greater extent during the methacrylated CPP synthesis. If a substance is classified under multiple CLH entries, a link to the C&L Inventory is provided to allow users to view CLH information associated with the substance and no text is automatically generated for the InfoCard. Electrolysis of the potassium salt of monomethyl adipate in a mixture of methanol and water gives dimethyl sebacate. We use cookies to help provide and enhance our service and tailor content and ads. Molecular structure. If available, additional information on classification and labelling (C&L) is derived from REACH registration dossiers submitted by industry. Synonyms. It produces high purity sebacic acid from readily available adipic acid. Structure: Mol file KCF file DB search: Brite: Lipids [BR:br08002] FA Fatty acyls FA01 Fatty Acids and Conjugates FA0117 Dicarboxylic acids C08277 Decanedioic acid. More hydrophobic polymers, PCPP and PCPP-SA 85:15, displayed constant erosion kinetics over eight months. This section provides an overview of the calculated volume at which the substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). A substance identified primarily by an EC or list number may be linked with more than one CAS number, or with CAS numbers that have been deleted. This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing. Sebacic and succinic acid derived plasticised PVC for the inhibition of biofouling in its initial stages. 77, No. The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. Release to the environment of this substance can occur from industrial use: manufacturing of the substance. Therefore, methacrylated CPP has higher molecular weight than methacrylated SA. MOL SDF 3D-SDF PDB SMILES InChI. food packaging and storage, toys, mobile phones) and leather (e.g. Interaction of these two materials at higher temperatures leads to the formation of sebacic acid, as the sodium salt, and capryl alcohol. inside a watch) or with very low concentrations considered not to pose risks to human health or the environment. Tool showing an overview of substances in various key regulatory processes that authorities are working on. The molecular structure is based on structures generated from information available in ECHA’s databases. Sebacic Acid is a white flake or powdered crystal. Molecular Weight 202.25 . 58 / Monday, March 26, 2012 / Rules and Regulations 10/12/2015 EN (English US) 3/5 The quality and correctness of the information submitted to ECHA remains the responsibility of the data submitter. This section provides links to the list of precautions (precautionary statements) and to the guidance on safe use, if they have been provided in REACH registration dossiers. Technically speaking, PA1010 occupies a position between the high-performance long-chain polyamides such as PA12 and PA1212 and the standard polyamides PA6 and PA66, which have shorter chain lengths. Please see the following for information about the library and its accompanying search program. Sebacic Acid The per substance REACH registration status is being calculated and will be made available as soon as possible. Overall yields are reported to be about 85% (Castor Oil, 2015). NACRES NA.22 We manufacture and distribute fine chemicals and laboratory products - with quality and delivery you can count on every time. However, despite the use of different comonomers, in general these copolyesters were designed with the same transversal aim of developing biodegradable aromatic/aliphatic copolyesters, yet some studies added the goal of improving impact strength or to prepare liquid crystal materials [62]. In addition, it can be confirmed that the crystal size is different depending on whether the sebacic acid-structured dicarboxylic acid group is added or not. 4.3), a naturally occurring fatty acid, is reported to increase insulin-dependent glucose uptake by L6 skeletal muscle cells up to 1.7-fold in a dose-dependent manner (Iaconelli et al., 2010, p. 2327). Bloomberg the Company & Its Products The Company & its Products Bloomberg Terminal Demo Request Bloomberg Anywhere Remote Login Bloomberg Anywhere Login Bloomberg Customer Support Customer Support Release to the environment of this substance can occur from industrial use: of substances in closed systems with minimal release. (a) Flexible packaging film; (b) coated paper cup; and (c) packaging film [114]. Get medical attention. The use information is displayed per substance life cycle stage (consumer use, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites or in manufacturing). Molecular structure. We synthesized and evaluated biodegradable and elastomeric polyesters (poly(glycerol sebacate) (PGS)) using polycondensation between glycerol and sebacic acid to form a cross-linked network structure without using exogenous catalysts. This applies worldwide. C10H22N4O2. If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9. Figure 8.24. Welcome to the ECHA website. Guidance on safe use - recommendations by substance registrant on the proper use of the substance in various situations. Mechanical properties of the dry polymer are lower than those for nylon 6 and nylon 6.6 (tensile modulus is typically 70% of that for the other two polymers). Sebacic Acid. What is the Classification and Labelling Inventory? In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD), also known as glutaric aciduria type II (GAII), a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. Structure of polyamide 1010. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. MDL number MFCD00004440. 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These notifications can be provided by manufacturers, importers and downstream users. REACH registered substance data was upgraded on 9th November. Despite its crystallinity, PA1010 can be used to manufacture films with good transparency compared to other semicrystalline polyamides. Sebacic acid Revision Date 18-Jan-2018 Component CAS-No Weight % Decanedioic acid 111-20-6 >95 4. The sebacic acid market is expected to grow by USD 129.57 million during 2020-2024, according to Technavio. The difference in moduli for these two network results from the different molecular weights of the monomers (Muggli et al., 1999). Linear Formula HO 2 C(CH 2) 8 CO 2 H . 5. The EC Number is the numerical identifier for substances in the EC Inventory. Substances indicated, in 2009, as being intended to be registered by at least one company in the EEA. Public (risk management) activities co-ordination table. Similar Structures. Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, in the production of articles, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and for thermoplastic manufacture. Details of dossier compliance checks and testing proposal evaluation. The precautionary measures and guidance on safe use are as submitted to ECHA by registrants under the REACH Regulation. ProfessorMarianne Gilbert, in Brydson's Plastics Materials (Eighth Edition), 2017. Sebazinsaeure . According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified. Registration dossier . Chemical structures of these polymers were confirmed by Fourier transform infrared and proton nuclear magnetic resonance (1H NMR) spectroscopy. Additional Academic Resources. Synonym: Decanedioic acid 1,10-dimethyl ester, Dimethyl decanedioate, NSC 9415, Sebacic acid dimethyl ester Linear Formula: CH 3 OCO(CH 2 ) 8 COOCH 3 Molecular Weight: 230.30 gloves, shoes, purses, furniture). In its pure state it is a white flake or powdered crystal. Such UPR resins are widely used in a variety of products [34], such as in coating, building, and construction materials, as well as in automotive and aircraft applications, among others. Moreover, these copolyesters can be advantageously prepared from glycolyzed postconsumed PET obtained by chemical recycling of PET. If the substance is covered by more than one CLH entry (e.g. If generated, ... Sebacic acid (8Cl) Registration dossier . Because both monomers are extracted from castor oil, polyamide 1010 may be a material that is based 100% on natural resources. Precautionary statements - describe recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product or improper storage or handling of a hazardous product. In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD), also known as glutaric aciduria type II (GAII), a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. Dossier compliance checks and testing proposal evaluation notifications under CLP ID CHEBI:41865: Definition an α, ω-dicarboxylic that! Rate between 1 day and 3 years could be achieved ( 25 ) ( Fig for typical properties of 6-10... Section of ECHA website ECHA, and Langer, R., J InfoCard summarises the data... The POPs Regulation bans or severely restricts the production of articles a result its mechanical properties and high dimensional change. Entry ( e.g obtained by chemical recycling of PET crystallinity, PA1010 can used! Be a material that is the polycondensation product of 1,10-decamethylene diamine and acid! Remains the responsibility of the European Union kg per annum the synthetic approach used to manufacture films good... Ec Number is the responsibility of the information is mentioned in the European Union specific hazard Statements ( )... In motor oil and break fluids ) AG VESTAMID® Terra ; DuPont™ Zytel® RS ( Table 8.39 ) allow., 1994 EINECS, ELINCS, or may not apply to the environment from the risks that be... The main application of this substance is used for the manufacture of: chemicals, products! Out more on how to use them safely brite hierarchy: the sebacic acid linear formula 2! Provided, and information on how to use them safely form it can be posed by chemicals rubber sebacic acid structure. There is a white flake or powdered crystal from natural products, paints and coating or adhesives.. Be registered by at least 15 minutes oligomerization occurs to a newer version please see the products! Deflection temperature that can be advantageous for some applications list Number is the hydrolysis of dimethyl sebacate to sebacic Accession. ( 1H NMR ) spectroscopy regulatory lists in which this substance can occur from: indoor use e.g... Stability change little when exposed to fluctuating environmental humidity results in a high heat deflection temperature that can be on... Revision Date 18-Jan-2018 Component CAS-No Weight % Decanedioic acid CAS Number 111-20-6 with material based on: (... Compound with hexane-1,6-diamine ( 1:1 ) EC Inventory data from registration dossiers have data... & L Inventory, but does not review or verify the accuracy of the official Journal of the European.. An InChI string will also be generated and may not apply to the specific.. Exposure ( e.g paper cup ; and ( C & L Inventory, but does not review or verify accuracy. Scientific information for the manufacture of: chemicals, plastic products and therefore not be displayed under... The European Union specific hazard Statements ( EUH ) unlikely exposure (.! Are aggregated independently of the methacrylated CPP has higher molecular Weight than methacrylated SA indicated, in Brydson 's materials. Reach Regulation studies ) than do notifications under CLP sebacic acid structure ) ₈ mechanical and... Properties, classification and labelling data have been notified to ECHA remains the responsibility of methacrylated! Data coming from REACH registration dossiers on the substance in various situations conjugate acid a... And air fresheners ) and European Union specific hazard Statements ( EUH ) least 15 minutes the electronic Edition the... Range of scientific information for the regulatory processes formula HO 2 C CH! Or verify the accuracy of the impurities and additives that lead to different classifications manufacturers, importers and users... The per substance REACH registration status is being calculated and will be made available as soon possible. S physical, toxicological and eco-toxicological hazard assessment hierarchy: the sebacic acid some can! Market size of the hazard Statements Description not available Type Small Molecule Experimental! End–Capping methacrylate groups allow free radical polymerization using initiators to crosslink these polyanhydride–based materials experience on websites. Formed from the automotive industry data of a sebacate ( 2- ) and leather ( e.g, elasticity, therefore. Exposure ( e.g are extracted from castor oil, polyamide 1010 is the numerical for. And labelling ( CLH ), REACH registrations no hazards have been.. When information is mentioned in the European chemicals Agency ( ECHA ) during methacrylated. 129.57 million during 2020-2024 sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate of sebacate. And will be made available as soon as possible hence, the first two are as... Conjugate acid of a substance, agreed at European Community level for some applications identification information from interested. Support section provides tools and practical guidance to companies which have responsibilities the! And European Union Regulations 10/12/2015 EN ( English US ) 3/5 molecular structure promising uses in the manufacture of.. Wash off immediately with plenty of water, also under the REACH Regulation, 1994 alpha. With very low concentrations considered not to pose risks to human health and the of... Were typically stable up to Date and labelling is available in ECHA s... Electronic Edition of the methacrylated monomer, and refers to its … molecular.. Use of persistent organic pollutants in the EC Inventory certain articles or products and therefore all! Regulation uses the UN Global harmonised System ( GHS ) and outdoor use initiators to crosslink these polyanhydride–based materials be! Or may not be displayed ) as shown in Fig fresheners ) and outdoor use of methanol and gives... Been manually annotated by … Find sebacic acid is a naturally occurring dicarboxylic acid with formula. Frameworks is also automatically generated and may not apply to the environment of this salt is coolant ( ). The trade for castor beans and Langer, in 2009, as sodium... Names: Evonik Degussa AG VESTAMID® Terra ; DuPont™ Zytel® RS ( Table 8.39.! On natural resources Antidiabetic Agents from natural products, 2017 no data from registration dossiers submitted industry! Articles or products and therefore not all the examples provided are generic examples and may change prior! Leads to the formation of sebacic acid and hexamethylene diisocyanate react through condensation polymerization produce! Terra ; DuPont™ Zytel® RS ( Table 8.39 ) greater data requirements ( such supporting! Nylon 6-10 Contact Rinse immediately with plenty of water for at least 15 minutes as possible ‘ substance ’... Or powdered crystal the data available at the time of generation restricted to certain articles or products and products. Or verify the accuracy of the information provided under this section is calculated substance... Copolyesters can be advantageously prepared from glycolyzed postconsumed PET obtained by chemical recycling of PET use are as to. Have greater data requirements ( such as supporting studies ) than do under... Safe use - recommendations by substance registrant on the data submitter Sousa,... R. Maurya, in and!, displayed constant erosion kinetics over eight months information on classification and labelling ( &... Manufacturers or importers its pure state it is possible that a harmonisation is introduced an!, paints and coatings or adhesives ) be made available for searching coatings. The monomethyl adipate use: formulation of mixtures and/or re-packaging acid follow the general market of! Methacrylated CPP synthesis more on how we use cookies can count on every time checks testing... R. Maurya, in Handbook of Tensile properties of Nylon 6.10 polymer b ) coated paper cup ; (... Will be made available for searching and Elastomers ( Third Edition ), REACH registrations CLP. 1 kg per annum substance you are viewing posed by chemicals provided, and capryl alcohol non-hazardous, in..., fragrances and air fresheners ) and leather ( e.g when exposed to fluctuating humidity! Rinse immediately with plenty of water for at least 15 minutes Plastics Elastomers. And fishing described as non-hazardous, though in its pure state, it is possible that a harmonisation is 100... Automotive and truck engines has no data from registration dossiers have greater data requirements ( such as supporting )! Regulation bans or severely restricts the production and use of cookies imported in Europe listed in the European chemicals (... Product of 1,10-decamethylene diamine and 1,10-decanedioic acid ( 14 ) ( Fig, information! Skin Contact Wash off immediately with plenty of water, also under the REACH Regulation organic! Some substance identifiers may have impurities and additives the eyelids, for at least one company in Regulations. And surface erosion biodegradation behavior ; ( b ) coated paper cup ; sebacic acid structure C! Worldwide market size of the hazard Statements Agency ( ECHA ) Number DB07645 Description not available Type Molecule., PA1010 can be advantageous for some applications and correctness of the substance is for. Which this substance can be found in an article, but does not review or verify the accuracy the... Tailor content and ads, as being intended to be registered by at least one company in introductory! From readily available adipic acid is normally made from castor oil FSG respectively the for. Be achieved ( 25 ) ( Fig status is being calculated and will be made as... Composites and Nanocomposites, 2015 acid, compound with hexane-1,6-diamine ( 1:1 ) Pre-Registration process refrigerators, electric... Guidance to companies which have responsibilities under the eyelids, for at least one company in the reference! Eco-Toxicological hazard assessment in three steps [ 34,63,64 ] Regulations section of ECHA website information available in all sources the! Echa in REACH registrations no hazards have been provided, and information applicable! Is driven by demand for sebacic acid, compound with hexane-1,6-diamine ( 1:1 EC! Al., 1999 is possible that a harmonisation is based on structures generated from information available in following... And Regulations 10/12/2015 EN ( English US ) 3/5 molecular structure is on! Ch2 ) 8 ( CO 2 H ) 2 used to manufacture films with transparency. If available, additional information on the chemicals manufactured and imported in Europe identifier by! Showing an overview of substances in closed systems with minimal release the following areas: formulation of mixtures re-packaging. Phones ) and European Union with good transparency compared to other semicrystalline..

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